Server error Loading this assembly would produce a different grant set from other instances

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SharePoint

Error after configuration Wizard

I am having the following after installing the Central admin

 

Loading this assembly would produce a different grant set from other instances

I changed the following key as I found it in the following link

https://www.ca.com/us/services-support/ca-support/ca-support-online/knowledge-base-articles.TEC1445538.html

Configure the following registry settings using regedit.exe:

Solution

Change assembly load optimization

In key ‘HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\.NETFramework‘, create a new ‘DWORD (32-bit) Value’ named “LoaderOptimization” with a value 1 (either in decimal or hexadecimal as they are the same).

 

 

And here also

HKEY_LOCAL_MACHINE\SOFTWARE\Wow6432Node\Microsoft\.NETFramework‘, create a new ‘DWORD (32-bit) Value’ named “LoaderOptimization” with a value 1 (either in decimal or hexadecimal as they are the same).

 

 

Note: restart the server

Now it’s working with me

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